OBJECTIVE: Nowadays recombinant factor VIII is produced in murine cells including in Chinese hamster ovary (CHO) and baby hamster kidney cells (BHK).Previous studies, using the murine leukemia virus-derived retroviral vector pMFG-FVIII-P140K, modified two recombinant human cell lines, HepG2 and Hek293 to produce recombinant factor VIII.In order Ant
Atrial flutter with 1:1 atrioventricular conduction is a cardiac arrhythmia difficult to diagnose, fatal in many cases, and unmanageable with drug therapy.A number of 17 Charms patients presenting with this disease was studied.A percentage of 70.6 % presented with throbbings, 64.7 % with syncope and important symptoms such as dizziness, sweating, a
Abstract Background Nijmegen breakage syndrome (NBS) is a rare genetic disorder inherited in an autosomal recessive pattern associated with an increased risk of developing lymphoproliferative disorders, mainly non-Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL).NBS patients are 50 times more likely to develop malignancy than healthy c
MHD solitons are studied in a model where the usual Vitamin B-1 Hall-MHD model is extended to include the finite Larmor radius (FLR) corrections to the pressure tensor.The resulting 4-dimensional set of differential equations is treated numerically.In this extended model, the point at infinity can be of several types.Necessary for the existence of